Gene name:
Kif5a (Kiaa4086;Kif5;Nkhc1) ;
Protein name:
Kinesin heavy chain isoform 5A ;
Alternative:
Neuronal kinesin heavy chain (NKHC) ;Kinesin heavy chain neuron-specific 1 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Oligomer composed of two heavy chains and two light chains (By similarity). Interacts with GRIP1.
Function:
Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL).
Subcellular Location:
Cytoplasm
perinuclear region
Cytoplasm
cytoskeleton
Concentrated in the cell body of the neurons, particularly in the perinuclear region.
Protein Attributes:
50:
MAETNNECSI | KVLCRFRPLN | QAEILRGDKF | IPIFQGDDSV | IIGGKPYVFD |
100:
RVFPPNTTQE | QVYHACAMQI | VKDVLAGYNG | TIFAYGQTSS | GKTHTMEGKL |
150:
HDPQLMGIIP | RIARDIFNHI | YSMDENLEFH | IKVSYFEIYL | DKIRDLLDVT |
200:
KTNLSVHEDK | NRVPFVKGCT | ERFVSSPEEI | LDVIDEGKSN | RHVAVTNMNE |
250:
HSSRSHSIFL | INIKQENVET | EQKLSGKLYL | VDLAGSEKVS | KTGAEGAVLD |
300:
EAKNINKSLS | ALGNVISALA | EGTKSYVPYR | DSKMTRILQD | SLGGNCRTTM |
350:
FICCSPSSYN | DAETKSTLMF | GQRAKTIKNT | ASVNLELTAE | QWKKKYEKEK |
400:
EKTKAQKETI | AKLEAELSRW | RNGENVPETE | RLAGEDSALG | AELCEETPVN |
450:
DNSSIVVRIA | PEERQKYEEE | IRRLYKQLDD | KDDEINQQSQ | LIEKLKQQML |
500:
DQEELLVSTR | GDNEKVQREL | SHLQSENDAA | KDEVKEVLQA | LEELAVNYDQ |
550:
KSQEVEEKSQ | QNQLLVDELS | QKVATMLSLE | SELQRLQEVS | GHQRKRIAEV |
600:
LNGLMRDLSE | FSVIVGNGEI | KLPVEISGAI | EEEFTVARLY | ISKIKSEVKS |
650:
VVKRCRQLEN | LQVECHRKME | VTGRELSSCQ | LLISQHEAKI | RSLTEYMQTV |
700:
ELKKRHLEES | YDSLSDELAR | LQAHETVHEV | ALKDKEPDTQ | DAEEVKKALE |
750:
LQMENHREAH | HRQLARLRDE | INEKQKTIDE | LKDLNQKLQL | ELEKLQADYE |
800:
RLKNEENEKS | AKLQELTFLY | ERHEQSKQDL | KGLEETVARE | LQTLHNLRKL |
850:
FVQDVTTRVK | KSAEMEPEDS | GGIHSQKQKI | SFLENNLEQL | TKVHKQLVRD |
900:
NADLRCELPK | LEKRLRATAE | RVKALEGALK | EAKEGAMKDK | RRYQQEVDRI |
950:
KEAVRYKSSG | KRGHSAQIAK | PVRPGHYPAS | SPTNPYGTRS | PECISYTNNL |
1000:
FQNYQNLHLQ | AAPSSTSDMY | FASSGATSVA | PLASYQKANM | DNGNATDIND |
1027:
NRSDLPCGYE | AEDQAKLFPL | HQETAAS
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
ELISA Kit for Mouse Kinesin heavy chain isoform 5A
ELISA Kit for Mouse Kinesin heavy chain isoform 5A
ELISA Kit for Mouse Kinesin heavy chain isoform 5A
CLIA Kit for Mouse Kinesin heavy chain isoform 5A
CLIA Kit for Mouse Kinesin heavy chain isoform 5A
CLIA Kit for Mouse Kinesin heavy chain isoform 5A
Polyclonal Antibody for Mouse Kinesin heavy chain isoform 5A
Polyclonal Antibody for Mouse Kinesin heavy chain isoform 5A
Polyclonal Antibody for Mouse Kinesin heavy chain isoform 5A
Monoclonal Antibody for Mouse Kinesin heavy chain isoform 5A
Monoclonal Antibody for Mouse Kinesin heavy chain isoform 5A
Monoclonal Antibody for Mouse Kinesin heavy chain isoform 5A
Protein for Mouse Kinesin heavy chain isoform 5A
Protein for Mouse Kinesin heavy chain isoform 5A
Protein for Mouse Kinesin heavy chain isoform 5A
R&D Technical Data
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Precision
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Recovery
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Linearity
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Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Brain .
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more...
Science309:1559-1563(2005)
[
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[
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[
Abstract ]
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6 .
strain :
C57BL/6J .
tissue :
Brain .
3.
"Prediction of the coding sequences of mouse homologues of KIAA gene. The complete nucleotide sequences of mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
Okazaki N.
,
Kikuno R.F.
,
Ohara R.
,
Inamoto S.
,
Nagase T.
,
Ohara O.
,
Koga H.
Submitted (2005-02) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Fetal brain .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6 .
tissue :
Brain .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 89-237
tissue :
Brain .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH GRIP1
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;DISRUPTION PHENOTYPE